ExCEEd Orphan Announces Extension of an Exclusive Distribution Agreement with Mirum Pharmaceuticals for Marketing and Distribution of LIVMARLI™ (maralixibat) to Additional CEE Countries

ExCEEd Orphan Distribution d.o.o., a Croatia based fully-owned subsidiary of ExCEEd Orphan s.r.o., a company providing full business solutions for the treatment of rare diseases, signed an extension of exclusive distribution agreement with Mirum Pharmaceuticals, Inc. for the distribution and marketing of LIVMARLI (maralixibat) in additional CEE countries. Consequently, ExCEEd Orphan will market and distribute LIVMARLI in 14 CEE countries including Albania, Bosnia & Hercegovina, Bulgaria, Croatia, Czechia, Hungary, Kosovo, Montenegro, North Macedonia, Poland, Romania, Serbia, Slovakia and Slovenia.

About LIVMARLI™ (maralixibat) oral solution

LIVMARLI™ (maralixibat) oral solution is an orally administered, once-daily, ileal bile acid transporter (IBAT) inhibitor approved by the FDA and EMA for the treatment of cholestatic pruritus in patients with Alagille syndrome one year of age and older.

About Alagille syndrome

Alagille syndrome (ALGS) is a rare genetic disorder in which bile ducts are abnormally narrow, malformed and reduced in number, which leads to bile accumulation in the liver and ultimately progressive liver disease. The estimated incidence of ALGS is one in every 30,000 people.  The accumulation of bile acids prevents the liver from working properly to eliminate waste from the bloodstream and, according to recent reports, 60% to 75% of patients with ALGS have a liver transplant before reaching adulthood.

About ExCEEd Orphan

ExCEEd Orphan was founded in 2018 by five rare disease experts from multiple Central and Eastern European (CEE) countries. The Company is focusing on innovative treatments for rare diseases and has extensive experience in launching innovative medicines in this field. The portfolio of ExCEEd Orphan includes products in therapeutic areas like haematology, neurology, immunology, and metabolic diseases.

For further information about ExCEEd Orphan please visit

About Mirum Pharmaceuticals, Inc.

Mirum Pharmaceuticals, Inc. is a biopharmaceutical company dedicated to transforming the treatment of rare liver diseases.

For further information about Mirum Pharmaceuticals please visit www.mirumpharma.com.

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